Prof. Aseem Ansari is a professor of Biochemistry in University of Wisconsin and Madison. He is also the founder of the Khorana and Bose programs that aim to foster long term partnerships and collaborations among the next generation of pioneers and innovators in science and technology.
The major goal of Prof. Aseem’s research is to create synthetic molecules that mimic natural transcription factors and can be tuned to counteract the actions of malfunctioning transcription factors. His lab integrates chemical, biological, biophysical, genomic and computational approaches create synthetic or artificial transcription factors (ATFs). ATFs may be engineered to control any gene regulatory circuit in a predetermined manner. In the long-term, his goal is to create synthetic molecules that can regulate desired circuitry to dictate a desired biological outcome, for example, the fate decisions of human embryonic stem cells.